Non believers often respond that even at the Last Supper,
the apostles did not sense that they had flesh in their hands
and blood in their cup. But Jesus is God. The creative literalness
of the words: "This is my body; this is my blood" must be
believed. God cannot lie. And God can turn bread into flesh
and wine into blood without the appearances of bread and wine
changing.
Medieval philosophers and theologians called this expression
of Divine Truth and Creative Power "transubstantiation". Yes,
God can change the substance of any created matter while
the appearances remain unchanged. And this demands faith.